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Leflunomides immunomodulatory activity derives from its action as a competitive inhibitor of the rate-limiting enzyme necessary for pyrimidine synthesis.
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Sources of funding for pharmaceutical research has come under scrutiny in the last decade as academic and government sources of funding have become increasingly scarce and the pharmaceutical industry has become the main source of research dollars. But the issue of objectivity has been raised, and some have even suggested that negative studies, that is studies that show a drug in an unfavorable light, may never be published. The American Medical Association has recently tackled this issue.
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The Advisory Committee on Immunization Practices (ACIP) recommends that children 6 to 23 months of age be vaccinated annually against influenza.
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Health care workers need an annual influenza vaccine to protect themselves and their patients, advise national infection control officials.
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Moving to clear up the considerable confusion of the last flu season, the Centers for Disease Control and Prevention has drafted new guidelines for health care workers who receive the live attenuated influenza vaccine.
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Home health managers may be overlooking the social importance of sharing meals or food with patients.
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The following publications and web sites provide information on cultural diversity and health care.
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Although the Centers for Medicare & Medicaid Services changed the rules governing flu and pneumococcal vaccines in 2002 to allow the use of standing orders for home health patients who receive the vaccines, most home health agencies still opt to obtain physician orders for each patient.
